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Table 3 Replication study: frequency of ischaemic heart disease in a second population of early rheumatoid arthritis patients stratified by TGFB1+868 SNP genotypes

From: Interaction between smoking and functional polymorphism in the TGFB1 gene is associated with ischaemic heart disease and myocardial infarction in patients with rheumatoid arthritis: a cross-sectional study

  Ischemic heart disease
TGFB1+868 (T/C) Negative Positive
TT 82 (93.2%) 6 (6.8%)
TC 118 (85.5%) 20 (14.5%)
CC 32 (97.0%) 1 (3.0%)
TT + TC versus CC OR = 2.86, 95% CI 0.53-5.46
TC versus TT + CC OR = 2.64, 95% CI 1.10-6.34a
  1. 'Negative' and 'positive' values are presented as number (percentage). aP = 0.022. CI, confidence interval; OR, odds ratio; SNP, single-nucleotide polymorphism; TGFB1, transforming growth factor-beta-1.