Skip to main content

Table 3 Replication study: frequency of ischaemic heart disease in a second population of early rheumatoid arthritis patients stratified by TGFB1+868 SNP genotypes

From: Interaction between smoking and functional polymorphism in the TGFB1 gene is associated with ischaemic heart disease and myocardial infarction in patients with rheumatoid arthritis: a cross-sectional study

 

Ischemic heart disease

TGFB1+868 (T/C)

Negative

Positive

TT

82 (93.2%)

6 (6.8%)

TC

118 (85.5%)

20 (14.5%)

CC

32 (97.0%)

1 (3.0%)

TT + TC versus CC

OR = 2.86, 95% CI 0.53-5.46

TC versus TT + CC

OR = 2.64, 95% CI 1.10-6.34a

  1. 'Negative' and 'positive' values are presented as number (percentage). aP = 0.022. CI, confidence interval; OR, odds ratio; SNP, single-nucleotide polymorphism; TGFB1, transforming growth factor-beta-1.
Back to article page

Arthritis Research & Therapy

ISSN: 1478-6362

Contact us