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Table 5 Replication study: association of the TGFB1+868 heterozygous genotype with ischaemic heart disease in early rheumatoid arthritis patients stratified by ever smoking

From: Interaction between smoking and functional polymorphism in the TGFB1 gene is associated with ischaemic heart disease and myocardial infarction in patients with rheumatoid arthritis: a cross-sectional study

Ischemic heart disease
Smoke/+868 TC Negative Positive OR (95% CI)
-/- 25 (92.6%) 2 (7.4%) 1.0 (referent)
-/+ 38 (95.0%) 2 (5.0%) 0.66 (0.11-4.10)
+/- 69 (94.5%) 4 (5.5%) 0.66 (0.13-3.31)
+/+ 67 (81.7%) 15 (18.3%) 2.34 (0.57-9.61)
    AP: 0.84 (0.14-1.53)
  1. 'Negative' and 'positive' values are presented as number (percentage). AP, the attributable proportion due to interaction; CI, confidence interval; OR, odds ratio; TGFB1, transforming growth factor-beta-1.