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Table 1 Association analysis of new variants

From: Identification of low-frequency TRAF3IP2 coding variants in psoriatic arthritis patients and functional characterization

Coding position Protein position Position hg19 Allele 871 PsA patients 931 control individuals P(Fisher Exact)
     n % n %  
c.105_106 InsACC p.Pro35dup 111913185 Ins 2 0.11 3 0.16 1
    WT 1,740 99.89 1,859 99.84  
c.281G > A (rs61756667) p.Ser94Asn 111913009 A 1 0.06 4 0.21 0.376
    G 1,737 99.94 1,858 99.79  
c.350C > T p.Ala117Val 111912940 T 1 0.06 0 0 0.483
    C 1,737 99.94 1,858 100.00  
c.649C > A p.Pro217Thr 111912641 A 18 1.03 10 0.54 0.127
    C 1,724 98.97 1,852 99.46  
c.691C > T p.Leu231Phe 111912599 T 2 0.11 1 0.05 0.613
    C 1,740 99.89 1,861 99.95  
c.746A > G p.Gln249Arg 111912544 G 1 0.06 0 0 0.483
    A 1,741 99.94 1,862 100.00  
c.1058G > C p.Gly353Ala 111896989 C 1 0.06 0 0 0.483
    G 1,741 99.94 1,862 100.00  
c.1184A > G p.Asn395Ser 111896863 G 3 0.17 7 0.38 0.346
    A 1,739 99.83 1,855 99.62  
  1. WT, wild type. Names, position on chromosome 6, and count/frequency of wild-type alleles/low-frequency alleles of new variants in PsA patients and control individuals are shown, as well as the P value of Fisher Exact test.