Table 1 Association analysis of new variants
Coding position | Protein position | Position hg19 | Allele | 871 PsA patients | 931 control individuals | P(Fisher Exact) | ||
|---|---|---|---|---|---|---|---|---|
n | % | n | % | |||||
c.105_106 InsACC | p.Pro35dup | 111913185 | Ins | 2 | 0.11 | 3 | 0.16 | 1 |
WT | 1,740 | 99.89 | 1,859 | 99.84 | ||||
c.281G > A (rs61756667) | p.Ser94Asn | 111913009 | A | 1 | 0.06 | 4 | 0.21 | 0.376 |
G | 1,737 | 99.94 | 1,858 | 99.79 | ||||
c.350C > T | p.Ala117Val | 111912940 | T | 1 | 0.06 | 0 | 0 | 0.483 |
C | 1,737 | 99.94 | 1,858 | 100.00 | ||||
c.649C > A | p.Pro217Thr | 111912641 | A | 18 | 1.03 | 10 | 0.54 | 0.127 |
C | 1,724 | 98.97 | 1,852 | 99.46 | ||||
c.691C > T | p.Leu231Phe | 111912599 | T | 2 | 0.11 | 1 | 0.05 | 0.613 |
C | 1,740 | 99.89 | 1,861 | 99.95 | ||||
c.746A > G | p.Gln249Arg | 111912544 | G | 1 | 0.06 | 0 | 0 | 0.483 |
A | 1,741 | 99.94 | 1,862 | 100.00 | ||||
c.1058G > C | p.Gly353Ala | 111896989 | C | 1 | 0.06 | 0 | 0 | 0.483 |
G | 1,741 | 99.94 | 1,862 | 100.00 | ||||
c.1184A > G | p.Asn395Ser | 111896863 | G | 3 | 0.17 | 7 | 0.38 | 0.346 |
A | 1,739 | 99.83 | 1,855 | 99.62 | ||||