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Table 3 Cytokine levels (pg/mL) in patients with PsA stratified by LN

From: Synovial cytokine expression in psoriatic arthritis and associations with lymphoid neogenesis and clinical features

  n (%) of positive patients All n = 42 LN+ n = 20 (47.6%) LN- n = 22 (52.4%) Wilcoxon P value
GM.CSF 4 (10%) 0 (0; 0) 0 (0; 0) 0 (0; 0) 0.051
IFN-γ 6 (14%) 0 (0; 0) 0 (0; 0) 0 (0; 0) 0.444
IL-1β 7 (7%) 0 (0; 0) 0 (0; 0) 0 (0; 0) 0.632
IL-2 21 (50%) 42 (0; 133) 0 (0; 151) 83 (0; 119) 0.851
IL-4 2 (2%) 0 (0; 0) 0 (0; 0) 0 (0; 0) 0.365
IL-5 19 (19%) 0 (0; 0) 0 (0; 0) 0 (0; 0) 0.440
IL-6 41 (98%) 1241 (503; 1,544) 1324 (764; 1,496) 1093 (258; 1,720) 0.462
IL-10 22 (52%) 4 (0; 13) 4.4 (0; 12) 0 (0; 14) 0.926
IL-12p70 0 0 (0; 0) 0 (0; 0) 0 (0; 0) NA
IL-13 4 (10%) 0 (0; 0) 0 (0; 0) 0 (0; 0) 0.348
IL-15 38 (91%) 114 (47; 197) 180 (109; 261) 62 (23; 115) 0.002
IL-17 11 26%) 0 (0; 20) 0 (0; 7) 0 (0; 26) 0.757
IL-17F 12 (29%) 0 (0; 12) 0 (0; 6) 0 (0; 12) 0.728
IL-21 19 (45%) 0 (0; 817) 0 (0; 773) 0 (0; 958) 0.591
IL-22 1 (2%) 0 (0; 0) 0 (0; 0) 0 (0; 0) 0.317
IL-23 15 (36%) 0 (0; 212) 0 (0; 190) 0 (0; 262) 0.758
IL-28A 0 0 (0; 0) 0 (0; 0) 0 (0; 0) NA
CCL20 34 (81%) 37 (6; 497) 23 (7; 284) 40 (1; 624) 0.752
TGF-β1 8 (19%) 0 (0; 0) 0 (0; 0) 0 (0; 446) 0.157
TNF-α 4 (10%) 0 (0; 0) 0 (0; 0) 0 (0; 0) 0.323
TNF-β 7 (17%) 0 (0; 0) 0 (0; 0) 0 (0; 0) 0.684
  1. Data are expressed as median (IQR). NA, not applicable.