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Table 1 Sample collections, proportion of women, frequencies of the three more informative AIMs and North/South score

From: Bias in effect size of systemic lupus erythematosus susceptibility loci across Europe: a case-control study

  DNA sample Women (%) AIM frequency (%) N/S score
Collectiona Control SLE Control SLE rs12913832 rs382259 rs6730157  
NL 180 104 59.4 86.5 83.0 77.6 72.5 100.0
BEb 106 147 93.5 90.5     
DE 95 90 n.a. 90 77.9 68.1 56.9 80.5
CZb 100 101 32 85.1     
SK 93 94 93.5 91.5 72.8 63.8 39.4 64.4
HU 95 95 48.4 90.4 63.4 59.6 39.0 54.9
ES, LCG 145 88 82.9 92 35.4 67.4 45.3 47.6
ES, OVD 200 147 69 91.8 30.5 70.4 45.4 47.2
ES, SCQ 95 109 48.4 96 35.1 68.2 41.3 46.0
ES, BCN 97 90 52.6 91.1 32.6 63.2 41.6 40.5
ES, MAD 281 92 68.8 91.3 33.1 61.9 42.3 40.0
PT 97 100 91.3 95.3 28.7 60.7 39.1 34.6
IT, MXP 106 129 42.5 86.8 47.6 49.1 19.8 26.2
IT, ROM 102 84 55.9 89.7 38.2 51.9 15.3 20.3
GR, AUMS 100 95 92 91.6 36.0 44.0 13.4 11.3
IT, NAP 109 79 100 90.1 38.6 42.2 10.0 9.6
GR, EH 100 98 67 86.7 36.7 38.0 13.5 6.8
  1. Collections are in descending order of N/S score. aCollections from: University Medical Center Groningen, The Netherlands (NL); Université Catholique de Louvain, Belgium (BE); Hannover Medical School, Germany (DE); Institute of Rheumatology, The Czech Republic (CZ); Martin Faculty Hospital, Slovakia (SK); Albert Szent-Györgyi Medical and Pharmaceutical Centre, Hungary (HU); Complexo Hospitalario Universitario A Coruña, Spain (ES, LCG); Hospital Universitario Central de Asturias, Spain (ES, OVD); Hospital Clinico Universitario de Santiago, Spain (ES, SCQ); Hospital Val d'Hebron of Barcelona, Spain (ES, BCN); Hospital 12 de Octubre, Madrid, Spain (ES, MAD); Hospital Garcia de Orta, Almada, Portugal (PT); University of Milan and Fondazione IRCCS Ospedale Maggiore Policlinico from Milan, Italy (IT, MXP), Ospedale S. Camillo - Forlanini from Roma, Italy (IT, ROM); Athens University Medical School, Athens, Greece (GR, AUMS); Second University of Naples, Italy (IT, NAP); and Evangelismos Hospital, Athens, Greece (GR, EH). bThese two collections were not analysed further because of differences in AIM frequencies between cases and controls.