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Table 4 Correlations between early change in bone resorption marker sCTX and clinical assessments at last follow-up

From: The effect of three years of TNF alpha blocking therapy on markers of bone turnover and their predictive value for treatment discontinuation in patients with ankylosing spondylitis: a prospective longitudinal observational cohort study

  Δ0 to 3 sCTX Z-score
Assessment at last follow-up a correlation P-value
BASDAI (range 0 to 10) -0.388 0.000
ASDASCRP -0.463 0.000
Physician's GDA (range 0 to 10) -0.321 0.001
Patient's GDA (range 0 to 10) -0.260 0.010
ESR (mm/h) -0.273 0.006
CRP (mg/l) -0.288 0.004
BASFI (range 0 to 10) -0.268 0.008
Chest expansion (cm) 0.260 0.010
Modified Schober test (cm) -0.031 0.762
Occiput to wall distance (cm) 0.095 0.350
Lateral lumbar flexion L (cm) 0.096 0.346
Lateral lumbar flexion R (cm) 0.169 0.097
ASQoL (range 0 to 18) -0.296 0.003
  1. Data of 105 AS patients were analyzed.
  2. See Tables 1 and 3 for abbreviations.
  3. a Defined as at three years of TNF-α blocking therapy or at the moment of treatment discontinuation