Figure 5From: Sensory and sympathetic nerve fibers undergo sprouting and neuroma formation in the painful arthritic joint of geriatric mice Histograms showing an increase in the density of sensory and sympathetic nerve fibers in the geriatric arthritic knee joint. The length of calcitonin gene-related peptide (CGRP+, A) sensory nerve fibers, neurofilament 200 kDa (NF200+, B) sensory nerve fibers, tyrosine hydroxylase (TH+, C) postganglionic sympathetic nerve fibers and growth-associated protein-43+ (GAP-43+, D) nerve fibers undergoing sprouting in the synovium were obtained by manually tracing the nerve fibers in a determined volume of synovium. Bars represent the mean of at least three mice ± SEM. *P < 0.05 versus mice that received intraarticular injections of saline.Back to article page