Serum adiponectin levels in systemic sclerosis (SSc). Sera from 129 patients with limited (lcSSc) or diffuse (dcSSc) cutaneous SSc and 86 controls were analyzed by multiplex assays. (a) Horizontal bars indicate median values in each group. (b) Correlation between adiponectin levels and modified Rodnan skin score (MRSS) in all patients with SSc (left panel) and patients with Scl-70-positive SSc (right panel). The solid line represents the linear regression line. (c) Adiponectin levels in patients with SSc according to disease duration (defined as duration from first non-Raynaud manifestation). Horizontal bars indicate median values.