Figure 4

Effects of resistin on peripheral blood mononuclear cells (PBMC). Resistin induces the release of IL-1α (a), IL-6 (b), MCP-1 (c) and TNFα (d) and reduces the release of perforin (e) and granzyme (f) from PBMCs into cell culture media after 48 hours. Bars represent the mean + SEM. P-values less than 0.05 were considered statistically significant; * P < 0.05,** P < 0.01, *** P < 0.001.