TY - JOUR AU - Lane, J. M. AU - Weiss, C. PY - 1975 DA - 1975// TI - Review of articular cartilage collagen research JO - Arthritis Rheum VL - 18 UR - https://doi.org/10.1002/art.1780180605 DO - 10.1002/art.1780180605 ID - Lane1975 ER - TY - JOUR AU - Billinghurst, R. C. AU - Dahlberg, L. AU - Ionescu, M. AU - Reiner, A. AU - Bourne, R. AU - Rorabeck, C. AU - Mitchell, P. AU - Hambor, J. AU - Diekmann, O. AU - Tschesche, H. AU - Chen, J. AU - Van Wart, H. AU - Poole, A. R. PY - 1997 DA - 1997// TI - Enhanced cleavage of type II collagen by collagenases in osteoarthritic articular cartilage JO - J Clin Invest VL - 99 UR - https://doi.org/10.1172/JCI119316 DO - 10.1172/JCI119316 ID - Billinghurst1997 ER - TY - JOUR AU - Konttinen, Y. T. AU - Mandelin, J. AU - Li, T. F. AU - Salo, J. AU - Lassus, J. AU - Liljeström, M. AU - Hukkanen, M. AU - Takagi, M. AU - Virtanen, I. AU - Santavirta, S. PY - 2002 DA - 2002// TI - Acidic cysteine endoproteinase cathepsin K in the degeneration of the superficial articular hyaline cartilage in osteoarthritis JO - Arthritis Rheum VL - 46 UR - https://doi.org/10.1002/art.10185 DO - 10.1002/art.10185 ID - Konttinen2002 ER - TY - JOUR AU - Dejica, V. M. AU - Mort, J. S. AU - Laverty, S. AU - Percival, M. D. AU - Antoniou, J. AU - Zukor, D. J. AU - Poole, A. R. PY - 2008 DA - 2008// TI - Cleavage of type II collagen by cathepsin K in human osteoarthritic cartilage JO - Am J Pathol VL - 173 UR - https://doi.org/10.2353/ajpath.2008.070494 DO - 10.2353/ajpath.2008.070494 ID - Dejica2008 ER - TY - JOUR AU - Connor, J. R. AU - LePage, C. AU - Swift, B. A. AU - Yamashita, D. AU - Bendele, A. M. AU - Maul, D. AU - Kumar, S. PY - 2009 DA - 2009// TI - Protective effects of a cathepsin K inhibitor, SB-553484, in the canine partial medial meniscectomy model of osteoarthritis JO - Osteoarthritis Cartilage VL - 17 UR - https://doi.org/10.1016/j.joca.2009.03.015 DO - 10.1016/j.joca.2009.03.015 ID - Connor2009 ER - TY - JOUR AU - Kozawa, E. AU - Nishida, Y. AU - Cheng, X. W. AU - Urakawa, H. AU - Arai, E. AU - Futamura, N. AU - Shi, G. P. AU - Kuzuya, M. AU - Hu, L. AU - Sasaki, T. AU - Ishiguro, N. PY - 2012 DA - 2012// TI - Osteoarthritic change is delayed in a cathepsin K knockout mouse model of osteoarthritis JO - Arthritis Rheum VL - 64 UR - https://doi.org/10.1002/art.33398 DO - 10.1002/art.33398 ID - Kozawa2012 ER - TY - JOUR AU - Svelander, L. AU - Erlandsson-Harris, H. AU - Astner, L. AU - Grabowska, U. AU - Klareskog, L. AU - Lindstrom, E. AU - Hewitt, E. PY - 2009 DA - 2009// TI - Inhibition of cathepsin K reduces bone erosion, cartilage degradation and inflammation evoked by collagen-induced arthritis in mice JO - Eur J Pharmacol VL - 613 UR - https://doi.org/10.1016/j.ejphar.2009.03.074 DO - 10.1016/j.ejphar.2009.03.074 ID - Svelander2009 ER - TY - JOUR AU - Kafienah, W. AU - Brömme, D. AU - Buttle, D. J. AU - Croucher, L. J. AU - Hollander, A. P. PY - 1998 DA - 1998// TI - Human cathepsin K cleaves native type I and II collagens at the N-terminal end of the triple helix JO - Biochem J VL - 331 UR - https://doi.org/10.1042/bj3310727 DO - 10.1042/bj3310727 ID - Kafienah1998 ER - TY - JOUR AU - Garnero, P. AU - Borel, O. AU - Byrjalsen, I. AU - Ferreras, M. AU - Drake, F. H. AU - McQueney, M. S. AU - Foged, N. T. AU - Delmas, P. D. AU - Delaissé, J. M. PY - 1998 DA - 1998// TI - The collagenolytic activity of cathepsin K is unique among mammalian proteinases JO - J Biol Chem VL - 273 UR - https://doi.org/10.1074/jbc.273.48.32347 DO - 10.1074/jbc.273.48.32347 ID - Garnero1998 ER - TY - JOUR AU - Kempson, G. E. AU - Muir, H. AU - Pollard, C. AU - Tuke, M. PY - 1973 DA - 1973// TI - The tensile properties of the cartilage of human femoral condyles related to the content of collagen and glycosaminoglycans JO - Biochim Biophys Acta VL - 297 UR - https://doi.org/10.1016/0304-4165(73)90093-7 DO - 10.1016/0304-4165(73)90093-7 ID - Kempson1973 ER - TY - JOUR AU - Bank, R. A. AU - Soudry, M. AU - Maroudas, A. AU - Mizrahi, J. AU - TeKoppele, J. M. PY - 2000 DA - 2000// TI - The increased swelling and instantaneous deformation of osteoarthritic cartilage is highly correlated with collagen degradation JO - Arthritis Rheum VL - 43 UR - https://doi.org/3.0.CO;2-E DO - 3.0.CO;2-E ID - Bank2000 ER - TY - JOUR AU - Miller, E. J. AU - Harris, E. D. AU - Chung, E. AU - Finch, J. E. AU - McCroskery, P. A. AU - Butler, W. T. PY - 1976 DA - 1976// TI - Cleavage of Type II and III collagens with mammalian collagenase: site of cleavage and primary structure at the NH2-terminal portion of the smaller fragment released from both collagens JO - Biochemistry VL - 15 UR - https://doi.org/10.1021/bi00649a009 DO - 10.1021/bi00649a009 ID - Miller1976 ER - TY - JOUR AU - Altman, R. AU - Asch, E. AU - Bloch, D. AU - Bole, G. AU - Borenstein, D. AU - Brandt, K. AU - Christy, W. AU - Cooke, T. D. AU - Greenwald, R. AU - Hochberg, M. PY - 1986 DA - 1986// TI - Development of criteria for the classification and reporting of osteoarthritis. Classification of osteoarthritis of the knee. Diagnostic and Therapeutic Criteria Committee of the American Rheumatism Association JO - Arthritis Rheum VL - 29 UR - https://doi.org/10.1002/art.1780290816 DO - 10.1002/art.1780290816 ID - Altman1986 ER - TY - JOUR AU - Poole, A. R. AU - Ionescu, M. AU - Fitzcharles, M. A. AU - Billinghurst, R. C. PY - 2004 DA - 2004// TI - The assessment of cartilage degradation in vivo: development of an immunoassay for the measurement in body fluids of type II collagen cleaved by collagenases JO - J Immunol Methods VL - 294 UR - https://doi.org/10.1016/j.jim.2004.09.005 DO - 10.1016/j.jim.2004.09.005 ID - Poole2004 ER - TY - JOUR AU - Miosge, N. AU - Hartmann, M. AU - Maelicke, C. AU - Herken, R. PY - 2004 DA - 2004// TI - Expression of collagen type I and type II in consecutive stages of human osteoarthritis JO - Histochem Cell Biol VL - 122 UR - https://doi.org/10.1007/s00418-004-0697-6 DO - 10.1007/s00418-004-0697-6 ID - Miosge2004 ER - TY - JOUR AU - Aigner, T. AU - Bertling, W. AU - Stöss, H. AU - Weseloh, G. AU - von der Mark, K. PY - 1993 DA - 1993// TI - Independent expression of fibril-forming collagens I, II, and III in chondrocytes of human osteoarthritic cartilage JO - J Clin Invest VL - 91 UR - https://doi.org/10.1172/JCI116303 DO - 10.1172/JCI116303 ID - Aigner1993 ER - TY - JOUR AU - Hollander, A. P. AU - Pidoux, I. AU - Reiner, A. AU - Rorabeck, C. AU - Bourne, R. AU - Poole, A. R. PY - 1995 DA - 1995// TI - Damage to type II collagen in aging and osteoarthritis starts at the articular surface, originates around chondrocytes, and extends into the cartilage with progressive degeneration JO - J Clin Invest VL - 96 UR - https://doi.org/10.1172/JCI118357 DO - 10.1172/JCI118357 ID - Hollander1995 ER - TY - JOUR AU - Wu, W. AU - Billinghurst, R. C. AU - Pidoux, I. AU - Antoniou, J. AU - Zukor, D. AU - Tanzer, M. AU - Poole, A. R. PY - 2002 DA - 2002// TI - Sites of collagenase cleavage and denaturation of type II collagen in aging and osteoarthritic articular cartilage and their relationship to the distribution of matrix metalloproteinase 1 and matrix metalloproteinase 13 JO - Arthritis Rheum VL - 46 UR - https://doi.org/10.1002/art.10428 DO - 10.1002/art.10428 ID - Wu2002 ER - TY - JOUR AU - Gallyas, F. AU - Merchenthaler, I. PY - 1988 DA - 1988// TI - Copper-H2O2 oxidation strikingly improves silver intensification of the nickel-diaminobenzidine (Ni-DAB) end-product of the peroxidase reaction JO - J Histochem Cytochem VL - 36 UR - https://doi.org/10.1177/36.7.2898497 DO - 10.1177/36.7.2898497 ID - Gallyas1988 ER - TY - JOUR AU - Loeser, R. F. PY - 2010 DA - 2010// TI - Age-related changes in the musculoskeletal system and the development of osteoarthritis JO - Clin Geriatr Med VL - 26 UR - https://doi.org/10.1016/j.cger.2010.03.002 DO - 10.1016/j.cger.2010.03.002 ID - Loeser2010 ER - TY - JOUR AU - Buckwalter, J. A. AU - Roughley, P. J. AU - Rosenberg, L. C. PY - 1994 DA - 1994// TI - Age-related changes in cartilage proteoglycans: quantitative electron microscopic studies JO - Microsc Res Tech VL - 28 UR - https://doi.org/10.1002/jemt.1070280506 DO - 10.1002/jemt.1070280506 ID - Buckwalter1994 ER - TY - JOUR AU - Aurich, M. AU - Mwale, F. AU - Reiner, A. AU - Mollenhauer, J. A. AU - Anders, J. O. AU - Fuhrmann, R. A. AU - Kuettner, K. E. AU - Poole, A. R. AU - Cole, A. A. PY - 2006 DA - 2006// TI - Collagen and proteoglycan turnover in focally damaged human ankle cartilage: evidence for a generalized response and active matrix remodeling across the entire joint surface JO - Arthritis Rheum VL - 54 UR - https://doi.org/10.1002/art.21535 DO - 10.1002/art.21535 ID - Aurich2006 ER - TY - JOUR AU - Leong, D. J. AU - Sun, H. B. PY - 2011 DA - 2011// TI - Events in articular chondrocytes with aging JO - Curr Osteoporos Rep VL - 9 UR - https://doi.org/10.1007/s11914-011-0070-3 DO - 10.1007/s11914-011-0070-3 ID - Leong2011 ER - TY - CHAP AU - Poole, A. R. AU - Guilak, F. AU - Abramson, S. B. ED - Moskowitz, R. W. ED - Altman, R. D. ED - Hochberg, M. C. ED - Buckwalter, J. A. ED - Goldberg, V. M. PY - 2007 DA - 2007// TI - Etiopathogenesis of osteoarthritis BT - Osteoarthritis, Diagnosis and Medical/Surgical Management PB - Wilkins CY - Philadelphia ID - Poole2007 ER - TY - JOUR AU - Kobayashi, M. AU - Squires, G. R. AU - Mousa, A. AU - Tanzer, M. AU - Zukor, D. J. AU - Antoniou, J. AU - Feige, U. AU - Poole, A. R. PY - 2005 DA - 2005// TI - Role of interleukin-1 and tumor necrosis factor alpha in matrix degradation of human osteoarthritic cartilage JO - Arthritis Rheum VL - 52 UR - https://doi.org/10.1002/art.20776 DO - 10.1002/art.20776 ID - Kobayashi2005 ER - TY - JOUR AU - Goldring, M. B. PY - 2000 DA - 2000// TI - Osteoarthritis and cartilage: the role of cytokines JO - Curr Rheumatol Rep VL - 2 UR - https://doi.org/10.1007/s11926-000-0021-y DO - 10.1007/s11926-000-0021-y ID - Goldring2000 ER - TY - JOUR AU - Dahlberg, L. AU - Billinghurst, R. C. AU - Manner, P. AU - Nelson, F. AU - Webb, G. AU - Ionescu, M. AU - Reiner, A. AU - Tanzer, M. AU - Zukor, D. AU - Chen, J. AU - van Wart, H. E. AU - Poole, A. R. PY - 2000 DA - 2000// TI - Selective enhancement of collagenase-mediated cleavage of resident type II collagen in cultured osteoarthritic cartilage and arrest with a synthetic inhibitor that spares collagenase 1 (matrix metalloproteinase 1) JO - Arthritis Rheum VL - 43 UR - https://doi.org/3.0.CO;2-8 DO - 3.0.CO;2-8 ID - Dahlberg2000 ER - TY - JOUR AU - Hou, W. S. AU - Li, Z. AU - Büttner, F. H. AU - Bartnik, E. AU - Brömme, D. PY - 2003 DA - 2003// TI - Cleavage site specificity of cathepsin K toward cartilage proteoglycans and protease complex formation JO - Biol Chem VL - 384 UR - https://doi.org/10.1515/BC.2003.100 DO - 10.1515/BC.2003.100 ID - Hou2003 ER - TY - JOUR AU - Vinardell, T. AU - Dejica, V. AU - Poole, A. R. AU - Mort, J. S. AU - Richard, H. AU - Laverty, S. PY - 2009 DA - 2009// TI - Evidence to suggest that cathepsin K degrades articular cartilage in naturally occurring equine osteoarthritis JO - Osteoarthritis Cartilage VL - 17 UR - https://doi.org/10.1016/j.joca.2008.07.017 DO - 10.1016/j.joca.2008.07.017 ID - Vinardell2009 ER - TY - JOUR AU - Degroot, J. AU - Verzijl, N. AU - Wenting-van Wijk, M. J. AU - Bank, R. A. AU - Lafeber, F. P. AU - Bijlsma, J. W. AU - TeKoppele, J. M. PY - 2001 DA - 2001// TI - Age-related decrease in susceptibility of human articular cartilage to matrix metalloproteinase-mediated degradation: the role of advanced glycation end products JO - Arthritis Rheum VL - 44 UR - https://doi.org/3.0.CO;2-1 DO - 3.0.CO;2-1 ID - Degroot2001 ER - TY - JOUR AU - Degroot, J. AU - Verzijl, N. AU - Jacobs, K. M. AU - Budde, M. AU - Bank, R. A. AU - Bijlsma, J. W. AU - TeKoppele, J. M. AU - Lafeber, F. P. PY - 2001 DA - 2001// TI - Accumulation of advanced glycation endproducts reduces chondrocyte-mediated extracellular matrix turnover in human articular cartilage JO - Osteoarthritis Cartilage VL - 9 UR - https://doi.org/10.1053/joca.2001.0469 DO - 10.1053/joca.2001.0469 ID - Degroot2001 ER - TY - JOUR AU - Christgau, S. AU - Garnero, P. AU - Fledelius, C. AU - Moniz, C. AU - Ensig, M. AU - Gineyts, E. AU - Rosenquist, C. AU - Qvist, P. PY - 2001 DA - 2001// TI - Collagen type II C-telopeptide fragments as an index of cartilage degradation JO - Bone VL - 29 UR - https://doi.org/10.1016/S8756-3282(01)00504-X DO - 10.1016/S8756-3282(01)00504-X ID - Christgau2001 ER - TY - JOUR AU - Lohmander, L. S. AU - Atley, L. M. AU - Pietka, T. A. AU - Eyre, D. R. PY - 2003 DA - 2003// TI - The release of crosslinked peptides from type II collagen into human synovial fluid is increased soon after joint injury and in osteoarthritis JO - Arthritis Rheum VL - 48 UR - https://doi.org/10.1002/art.11326 DO - 10.1002/art.11326 ID - Lohmander2003 ER - TY - JOUR AU - Charni, N. AU - Juillet, F. AU - Garnero, P. PY - 2005 DA - 2005// TI - Urinary type II collagen helical peptide (HELIX-II) as a new biochemical marker of cartilage degradation in patients with osteoarthritis and rheumatoid arthritis JO - Arthritis Rheum VL - 52 UR - https://doi.org/10.1002/art.20930 DO - 10.1002/art.20930 ID - Charni2005 ER - TY - JOUR AU - Zhen, E. Y. AU - Brittain, I. J. AU - Laska, D. A. AU - Mitchell, P. G. AU - Sumer, E. U. AU - Karsdal, M. A. AU - Duffin, K. L. PY - 2008 DA - 2008// TI - Characterization of metalloprotease cleavage products of human articular cartilage JO - Arthritis Rheum VL - 58 UR - https://doi.org/10.1002/art.23654 DO - 10.1002/art.23654 ID - Zhen2008 ER -