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Figure 3 | Arthritis Research & Therapy

Figure 3

From: Increased type II collagen cleavage by cathepsin K and collagenase activities with aging and osteoarthritis in human articular cartilage

Figure 3

Immunostaining of cartilage from young normal individuals. Sections of human femoral condylar cartilage from six non-OA individuals (ages 19 to 47 years), showing detection of neoepitopes generated by collagenases (C1,2C and C2C) and cathepsin K (C2K) in type II collagen. Specimens are positioned so that the articular surface is at the top of each figure. Bar = 200 μm.

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