Figure 5From: Increased type II collagen cleavage by cathepsin K and collagenase activities with aging and osteoarthritis in human articular cartilage Immunostaining of cartilage from osteoarthritic patients. Sections of human femoral condylar cartilage from six OA patients (ages 55 to 70 years), showing detection of neoepitopes generated by collagenases (C1,2C and C2C) and cathepsin K (C2K) in type II collagen. Bar = 200 μm.Back to article page