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Table 3 Linear regression analysis for general and RA disease-related characteristics and endothelial function in RA patients from the cross-sectional study

From: The role of inflammation and cardiovascular disease risk on microvascular and macrovascular endothelial function in patients with rheumatoid arthritis: a cross-sectional and longitudinal study

  Microvascular function Macrovascular function
  Endothelium-dependent Endothelium- independent Endothelium- dependent Endothelium- independent
RA disease-related characteristics     
   Disease duration β = -0.12, P = 0.29 β = 0.21, P = 0.07 β = -0.04 P = 0.76 β = -0.12, P = 0.34
   LogCRP β = -0.61, P = 0.05 β = 0.10, P = 0.32 β = 0.15, P = 0.13 β = 0.00, P = 0.97
   LogESR β = -0.09, P = 0.41 β = 0.18, P = 0.10 β = -0.01, P = 0.95 β = -0.08, P = 0.46
   DAS28 β = 0.15, P = 0.15 β = 0.02, P = 0.84 β = 0.06, P = 0.59 β = -0.01, P = 0.93
General characteristics     
   Age β = -0.37, R2 = 0.135c β = -0.20, R2 = 0.042a β = -0.24, R2 = 0.55a β = -0.36, R2 = 0.126c
   BMI β = 0.21, P = 0.05 β = 0.08, P = 0.41 β = -0.12, P = 0.26 β = -0.21, P = 0.05
   Resting SBP β = -0.11, P = 0.30 β = -0.02, P = 0.88 β = -0.11, P = 0.27 β = -0.27, R2 = 0.066b
   Resting DBP β = 0.04, P = 0.67 β = 0.08, P = 0.44 β = -0.12, P = 0.25 β = -0.05, P = 0.61
  1. RA disease-related characteristics and general characteristics were entered as independent variables, whereas microvascular and macrovascular endothelial functions were entered as dependent variables in the regression analysis. BMI, body mass index; CRP, C-reactive protein; DAS28, disease activity score in 28 joints; DBP, diastolic blood pressure; ESR, erythrocyte sedimentation rate; SBP, systolic blood pressure. aP < 0.05; bP < 0.01; cP < 0.001. R2 value is shown for all significant associations only.