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Table 6 Endothelial function during treatment in the longitudinal study

From: The role of inflammation and cardiovascular disease risk on microvascular and macrovascular endothelial function in patients with rheumatoid arthritis: a cross-sectional and longitudinal study

 

Baseline

2 weeks

12 weeks

Treatment effect

Degrees of freedom

Microvascular function

     

   Endothelium-dependent (Ach%)

314 ± 214

423 ± 250a

348 ± 209b

F = 5.09, P = 0.01

2, 21

   Endothelium-independent (SNP%)

247 ± 126

284 ± 147

261 ± 152

F = 1.18, P = 0.32

2, 21

Macrovascular function

     

   Endothelium-dependent (FMD%)

9.4 ± 6.8

12.0 ± 10.0

12.0 ± 8.1

F = 1.60, P = 0.21

2, 19

   Endothelium-independent (GTN%)

22 ± 7.4

23 ± 7.2

24 ± 7.2

F = 0.31, P = 0.74

2, 19

  1. Results are expressed as mean ± standard deviation. aDifferent from baseline. bDifferent from 2 weeks. Ach, acetylcholine; FMD, flow-mediated dilatation; GTN, glyceryl trinitrate-mediated dilatation; SNP, sodium nitroprusside.