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Table 6 Endothelial function during treatment in the longitudinal study

From: The role of inflammation and cardiovascular disease risk on microvascular and macrovascular endothelial function in patients with rheumatoid arthritis: a cross-sectional and longitudinal study

  Baseline 2 weeks 12 weeks Treatment effect Degrees of freedom
Microvascular function      
   Endothelium-dependent (Ach%) 314 ± 214 423 ± 250a 348 ± 209b F = 5.09, P = 0.01 2, 21
   Endothelium-independent (SNP%) 247 ± 126 284 ± 147 261 ± 152 F = 1.18, P = 0.32 2, 21
Macrovascular function      
   Endothelium-dependent (FMD%) 9.4 ± 6.8 12.0 ± 10.0 12.0 ± 8.1 F = 1.60, P = 0.21 2, 19
   Endothelium-independent (GTN%) 22 ± 7.4 23 ± 7.2 24 ± 7.2 F = 0.31, P = 0.74 2, 19
  1. Results are expressed as mean ± standard deviation. aDifferent from baseline. bDifferent from 2 weeks. Ach, acetylcholine; FMD, flow-mediated dilatation; GTN, glyceryl trinitrate-mediated dilatation; SNP, sodium nitroprusside.