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Table 1 Characteristics of patients in the study

From: T-cell autoreactivity to citrullinated autoantigenic peptides in rheumatoid arthritis patients carrying HLA-DRB1 shared epitope alleles

Patient Ethnicity HLA-DRB1 genotype ACPA Disease duration (years) Treatment C-reactive proteina (mg/l) Representation
RA1 Caucasian 03,0401 + 6 M, S 8 Figure 1
RA2 Caucasian 03, 0401 + < 1 Nil 3 Figures 1 to 5
RA3 Caucasian/Pacific Islander 0403, 0405 - < 1 M, S, H 3 Figure 1
RA4 Caucasian 0401, 0404 + < 1 L 11 Figures 1 to 5
RA5 Caucasian 0404, 1302 + 1 M, S, H 2 Figure 1
RA6 Caucasian 0401 13 + > 5 M, H 1 Figures 1 to 5
RA7 Asian 0405 - 1 M 1 Figures 1 to 5
RA8 Caucasian 0401, 0404 + > 5 L, H, S 22 Figures 1 to 5
RA9 Caucasian 0103, 0101 + < 1 Nil 4 Figures 1 to 5
RA10 Caucasian 01, 1302 + 5 H 10 Figures 1 to 5
RA11 Caucasian 04, 0301 - 4 M, S, H 3 Figures 1 to 5
RA12 Caucasian 0401 + 0 Nil 45 Figures 1 to 5
RA13 Caucasian 0101, 1301 - > 5 M 20 Figures 1 to 6
RA14 Caucasian 0408, 11 + > 5 M, S, H 4.6 Figures 1 to 6
RA15 Caucasian 0401, 0408 + 0 Nil 1 Figures 1 to 6
RA16 Caucasian 0101, 0408 + 0 Nil 6 Figures 1 to 6
RA17 Caucasian 0401, 03 + > 5 M, A 33 Figure 6
RA18 Caucasian 0401, 03 + 3 M 2 Figures 1 to 5
RA19 Caucasian 0101, 0103 + 2 M, S, H 5.3 Figures 1 to 5
RA20 Caucasian 0401, 1501 + 2 - 9.9 Figures 1 to 5
RA21 Caucasian 0401, 0101 + > 5 M, P 2 Figures 1 to 5
HC1 Caucasian 01 -     Figures 1 to 5
HC2 Caucasian 03, 04 -     Figures 1 to 5
HC3 Caucasian 0401, 0701 -     Figures 1 to 5
HC4 Caucasian 0101, 08 -     Figures 1 to 5
HC5 Caucasian 1301, 0401 -     Figures 1 to 6
HC6 Caucasian 0401, 1301 -     Figures 1 to 6
  1. A, abatacept; ACPA, anti-citrullinated peptide antibody; H, hydroxychloroquine; L, leflunomide; M, methotrexate; S, sulfasalazine; P, prednisone. For rheumatoid arthritis (RA) patients, mean age is 50 (range 22 to 65), 90% female; for healthy control (HC) individuals, mean age is 38 (40 to 45), 50% female. aMeasured at the time of blood withdrawal for peptide response.