TY - JOUR AU - Haas, Stefanie AU - Straub, Rainer H. PY - 2012 DA - 2012/05/23 TI - Disruption of rhythms of molecular clocks in primary synovial fibroblasts of patients with osteoarthritis and rheumatoid arthritis, role of IL-1β/TNF JO - Arthritis Research & Therapy SP - R122 VL - 14 IS - 3 AB - Circadian rhythms play an important role in the body and in single cells. Rhythms of molecular clocks have not been investigated in synovial fibroblasts (SF) of patients with osteoarthritis (OA) and rheumatoid arthritis (RA). The study was initiated to fill this gap and to study effects of interleukin (IL)-1β/tumor necrosis factor (TNF) on rhythmicity in synovial fibroblasts of RA and OA patients. SN - 1478-6354 UR - https://doi.org/10.1186/ar3852 DO - 10.1186/ar3852 ID - Haas2012 ER -