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Table 3 Unadjusted mean leptin by sex for hand osteoarthritis status and potential confounders in NHANES III

From: The relationship between hand osteoarthritis and serum leptin concentration in participants of the Third National Health and Nutrition Examination Survey

  Male Female
  n Meana (95% CI) n Meana (95% CI)
Overall 510 7.66 (7.11, 8.21) 546 19.24 (17.19, 21.29)
Hand OA status     
   Symptomatic hand OA 36 7.38 (5.31, 9.46) 54 21.55 (17.08, 26.02)
   Asymptomatic hand OA 159 6.69 (5.19, 8.18) 217 17.09 (15.00, 19.18)
   No hand OA 315 8.22 (7.47, 8.97) 275 20.77 (18.01, 23.53)
Age     
   60 to 69 years 255 7.53 (6.83, 8.22) 233 21.43 (18.73, 24.13)
   70 to 79 years 147 7.88 (6.47, 9.29) 197 17.60 (14.47, 20.73)
   80+ years 108 7.66 (6.24, 9.07) 116 16.00 (12.73, 19.28)
Race/ethnicity     
   Non-Hispanic white 273 7.62 (7.06, 8.17) 326 18.73 (16.52, 20.95)
   Non-Hispanic black 89 7.30 (5.61, 8.99) 101 24.39 (21.52, 27.25)
   Hispanic 139 8.74 (6.24, 11.25) 115 19.34 (13.94, 24.74)
   Other 9 7.42 (6.31, 8.53) 4 19.83 (-2.88, 42.54)
BMI status     
   Normal (BMI < 25 kg/m2) 183 5.00 (4.30, 5.70) 199 11.54 (10.30, 12.77)
   Overweight (25 ≤ BMI < 30 kg/m2) 217 7.73 (6.75, 8.70) 179 19.65 (17.68, 21.63)
   Obese (BMI ≥ 30 kg/m2) 90 13.03 (11.03, 15.03) 118 34.55 (31.22, 37.88)
Radiographic knee OA     
   Yes 132 8.99 (7.53, 10.45) 211 23.31 (19.55, 27.08)
   No 357 7.09 (6.59, 7.60) 315 16.93 (14.99, 18.87)
Diabetes     
   Yes 64 8.69 (7.10, 10.27) 72 20.62 (16.47, 24.76)
   No 445 7.55 (7.02, 8.08) 473 19.1 (17.13, 21.08)
Total cholesterol     
   Desirable (< 200) 201 7.24 (6.33, 8.14) 136 14.87 (12.01, 17.73)
   Borderline high (200 to 239) 193 7.36 (6.66, 8.07) 197 18.99 (16.40, 21.58)
   High (≥ 240) 113 8.18 (6.92, 9.44) 204 22.20 (18.99, 25.41)
  1. BMI, body mass index; CI, confidence interval; OA, osteoarthritis. aMeans are weighted using Third National Health and Nutrition Examination Survey (NHANES III) sampling weights.