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Table 2 The top 10 upregulated genes in aggregates of MSCs

From: Properties and usefulness of aggregates of synovial mesenchymal stem cells as a source for cartilage regeneration

No.

Genebank No.

Gene name

Symbol

fold change

1

AA583044

bone morphogenetic protein 2

BMP2

273

2

NM_002421

matrix metalloproteinase 1

MMP1

205

3

NM_000439

proprotein convertase subtilisin/kexin type 1

PCSK1

179

4

M86849

gap junction protein, beta 2

GJB2

170

5

M83248

secreted phosphoprotein 1 (osteopontin)

SPP1

156

6

L27624

tissue factor pathway inhibitor 2

TFPI2

137

7

NM_002422

matrix metalloproteinase 3

MMP3

136

8

N95414

integrin, alpha 2 (CD49B)

ITGA2

129

9

AW003173

stanniocalcin 1

STC1

124

10

AJ224869

chemokine (C-X-C motif) receptor 4

CXCR4

101

  1. The top 10 genes which increased higher in aggregates of MSCs cultured in hanging drops for three days compared with MSCs in a monolayer culture.
  2. Values are the means among three individual donors.