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Figure 1 | Arthritis Research & Therapy

Figure 1

From: Interleukin-7-aggravated joint inflammation and tissue destruction in collagen-induced arthritis is associated with T-cell and B-cell activation

Figure 1

Interleukin (IL)-7 enhances the severity of collagen-induced arthritis. Mice were injected with either phosphate-buffered saline (PBS) or IL-7, every other day starting at day 21 and continuing until day 33, and arthritis severity was graded. IL-7 significantly increased arthritis severity compared with that in PBS-treated mice (on average from days 27 to 33 by 135% ± 46% (A). IL-7 did not significantly change arthritis incidence (B). Values are expressed as mean ± SEM of 15 mice per group. ***Statistical difference of P < 0.001 for area under the curve (A).

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Arthritis Research & Therapy

ISSN: 1478-6362

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