Figure 4

Expression of Semaphorin 3A on CD19⁺CD25^high B cells. (A) demonstrates the MFI of CD19⁺CD25^highSema3A⁺ expression on B cells in whole blood from SLE patients compared to that of healthy controls (4.27 ± 0.47 versus 2.68 ± 0.09, P = 0.019). (B) is a representative histogram of the lower sema3A expression on B cells from SLE patients compared to that in healthy controls. The blank histogram represents the isotype control. MFI, mean fluorescence intensity; SLE, systemic lupus erythematosis.