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Table 2 IFN-γ levels in the tuberculosis antigen-stimulated wells and mitogen-stimulated wells that were used as positive controls

From: Quantiferon-TB Gold in tube assay for the screening of tuberculosis before and during treatment with tumor necrosis factor alpha antagonists

 

RA-TNF1 (n= 38)

RA-TNF2 (n= 38)

TNF-naive RA

(n= 40)

TB

(n= 30)

Leprosy

(n= 23)

Healthy controls (n= 41)

IFN-γ level in tuberulosis antigen well (IU/ml)

3.6 ± 8.4

3.0 ± 6.2

2.8 ± 5

2.3 ± 4.2

7.3 ± 8.0

3.5 ± 6.4

IFN-γ level in positive control well (IU/ml)

7.0 ± 6.4

16.1 ± 14.2a

8.7 ± 6.1

11.6 ± 12.1

12.2 ± 6.1

17.3 ± 6.4

  1. aThe mitogen-nil level increased significantly (P < 0.001) after treatment with TNF-α antagonists.