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Table 2 Pooled analysis of CD40LG polymorphisms in female SSc patients and controls

From: Analysis of the association between CD40 and CD40 ligand polymorphisms and systemic sclerosis

SNP Change Samples set N Minor allele,
no. (frequency)
Pvalue OR [95% CI] P_BD
rs3092952 G/A Controls 1,795 655 (0.176)    
   SSc 2,082 735 (0.186) 0.440 0.96 [0.85-1.07] 0.18
   lcSSc 1,446 515 (0.188) 0.592 0.97 [0.85-1.10] 0.12
   dcSSc 635 219 (0.179) 0.307 0.92 [0.77-1.09] 0.73
   ACA + 924 338 (0.195) 0.978 1.00 [0.87-1.16] 0.06
   ATA + 533 184 (0.188) 0.375 0.92 [0.77-1.11] 0.50
   Pulmonary fibrosis 542 198 (0.173) 0.735 0.97 [0.81-1.16] 0.41
rs3092920 T/G Controls 1,789 376 (0.107)    
   SSc 2,104 426 (0.105) 0.565 0.96 [0.83-1.11] 0.89
   lcSSc 1,456 310 (0.112) 0.929 1.01 [0.86-1.18] 0.97
   dcSSc 647 116 (0.091) 0.120 0.84 [0.67-1.05] 0.36
   ACA + 939 201 (0.111) 0.924 1.01 [0.84-1.21] 0.48
   ATA + 541 106 (0.103) 0.434 0.91 [0.73-1.15] 0.86
   Pulmonary fibrosis 549 124 (0.106) 0.657 1.05 [0.84-1.31] 0.55
  1. Controls are used as reference for all comparisons. All P values have been calculated for the allelic model by using the Mantel-Haenszel test under fixed effect. P_BD, P value by the Breslow-Day method.