From: Analysis of the association between CD40 and CD40 ligand polymorphisms and systemic sclerosis
SNP | Change | Samples set | N | Minor allele, no. (frequency) | Pvalue | OR [95% CI] | P_BD |
---|---|---|---|---|---|---|---|
rs3092952 | G/A | Controls | 1,795 | 655 (0.176) | |||
SSc | 2,082 | 735 (0.186) | 0.440 | 0.96 [0.85-1.07] | 0.18 | ||
lcSSc | 1,446 | 515 (0.188) | 0.592 | 0.97 [0.85-1.10] | 0.12 | ||
dcSSc | 635 | 219 (0.179) | 0.307 | 0.92 [0.77-1.09] | 0.73 | ||
ACA + | 924 | 338 (0.195) | 0.978 | 1.00 [0.87-1.16] | 0.06 | ||
ATA + | 533 | 184 (0.188) | 0.375 | 0.92 [0.77-1.11] | 0.50 | ||
Pulmonary fibrosis | 542 | 198 (0.173) | 0.735 | 0.97 [0.81-1.16] | 0.41 | ||
rs3092920 | T/G | Controls | 1,789 | 376 (0.107) | |||
SSc | 2,104 | 426 (0.105) | 0.565 | 0.96 [0.83-1.11] | 0.89 | ||
lcSSc | 1,456 | 310 (0.112) | 0.929 | 1.01 [0.86-1.18] | 0.97 | ||
dcSSc | 647 | 116 (0.091) | 0.120 | 0.84 [0.67-1.05] | 0.36 | ||
ACA + | 939 | 201 (0.111) | 0.924 | 1.01 [0.84-1.21] | 0.48 | ||
ATA + | 541 | 106 (0.103) | 0.434 | 0.91 [0.73-1.15] | 0.86 | ||
Pulmonary fibrosis | 549 | 124 (0.106) | 0.657 | 1.05 [0.84-1.31] | 0.55 |