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Figure 2 | Arthritis Research & Therapy

Figure 2

From: Hydroxychloroquine is associated with impaired interferon-alpha and tumor necrosis factor-alpha production by plasmacytoid dendritic cells in systemic lupus erythematosus

Figure 2

pDCs from SLE patients show impaired production of IFN-α and TNF-α after TLR-9/7 stimulation. Comparison of the frequency of circulating pDCs (CD123+ cells) producing IFN-α (left) and TNF-α (right) after TLR-9 (A) or TLR-7 (B) stimulation between SLE subjects (n = 39, white circles) and healthy controls (n = 10, black circles). In each case, the lines represent the mean value and the error bars show the standard deviation.

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