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Figure 4 | Arthritis Research & Therapy

Figure 4

From: Hydroxychloroquine is associated with impaired interferon-alpha and tumor necrosis factor-alpha production by plasmacytoid dendritic cells in systemic lupus erythematosus

Figure 4

pDC production of IFN-α/TNF-α upon TLR-9/7 stimulation in SLE subjects treated with HCQ. Comparison of the frequency of pDCs (CD123+ cells) producing IFN-α (left) and TNF-α (right) after TLR-9 (A) or TLR-7 (B) stimulation between SLE subjects that were treated (n = 25, white squares) or not (n = 14, black triangles) with HCQ. In each case, the lines represent the mean value and the error bars show the standard deviation.

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Arthritis Research & Therapy

ISSN: 1478-6362

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