Figure 4
From: Expression of interleukin-18 receptor in fibroblast-like synoviocytes
Expression of intercellular adhesion molecule (ICAM)-1 in fibroblast-like synoviocytes (FLS) (a) and U937 cells (b) upon stimulation with IL-18 (x-axis: staining intensity; y-axis: number of events). Broken and continuous lines show ICAM-1 expression in control conditions and IL-18-stimulated cells, respectively. The strongest induction of ICAM-1 by IL-18 (a) was 95.1, versus 73.9 in controls (ΔMFI = +28.6%), and (b) 82.1, versus 31.7 in U937 cells (ΔMFI = +159%). The result of each one of three similar independent experiments is represented. CD54PE = fluorescence intensity of cells, stained with phycoerythrin-labeled CD54 monoclonal antibodies; MFI = mean fluorescence intensity.