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Table 1 Participant characteristics at baseline assessment

From: Anti-tumour necrosis factor alpha therapy improves insulin sensitivity in normal-weight but not in obese patients with rheumatoid arthritis

 

Normal Weight (n= 16)

Obese (n= 16)

 

+IR

-IR

+IR

-IR

N (females)

8 (5)

8 (5)

8 (6)

8 (6)

Anti-TNFα agent (Infliximab/Etanercept/Adalimumab)

5/3/0

4/3/1

6/2/0

5/3/0

Smokers (current; ex)

3 (1; 2)

4 (1; 3)

3 (2; 1)

4 (2; 2)

Age (years)

60.8

62.2

58.6

60.8

 

(6.9)

(7.8)

(6.7)

(8.0)

Height (cm)

165.9

167

165.4

165.2

 

(10.6)

(12.2)

(11.9)

(9.4)

Weight (kg)

60.3

61.6

88.9

89.8

 

(6.4)

(7.2)

(10.1)

(9.6)

BMI (kg/m 2 )

21.8

22.1

32.3

32.8

 

(2.4)

(2.2)

(3.0)

(3.1)

HOMA

2.9

2.2*

3.1

2.1#

 

(0.7)

(0.4)

(0.5)

(0.8)

QUICKI

0.29

0.36*

0.30

0.37#

 

(0.02)

(0.03)

(0.03)

(0.01)

HAQ

1.6

1.8

1.7

2.0

 

(0.3)

(0.2)

(0.4)

(0.5)

DAS

5.7

5.9

6.2

6.1

 

(0.7)

(0.5)

(1.0)

(0.6)

ESR (mm/h)

31

38

35

43

 

(7.5)

(10)

(9.5)

(12.5)

CRP (mg/L)

29

32.5

31.4

34.2

 

(6.4)

(8.2)

(8.8)

(7.4)

Disease Duration

9.1

8.6

8

10.2

(years)

(2.5)

(2.3)

(3.6)

(4.7)

  1. * Significantly different compared to N+IR (P < 0.05). # Significantly different compared to O+IR (P < 0.05). BMI, body mass index; CRP, C-reactive protein; DAS, disease activity score 28; ESR, erythrocyte sedimentation rate; HAQ, Health Assessment Questionnaire; +IR, with insulin resistance; -IR, without insulin resistance; HOMA, Homeostasis Model Assessment Of Insulin Resistance; QUICKI, Quantitative Insulin Sensitivity Check Index