Skip to main content

Table 4 Correlation of changes in IGF-1, pain, and pain threshold, and changes in cerebrospinal markers

From: Changes in pain and insulin-like growth factor 1 in fibromyalgia during exercise: the involvement of cerebrospinal inflammatory factors and neuropeptides

  ΔIGF-1 (serum) ΔPain threshold ΔPain
  0.495 0.539 0.075
ΔCSF SP P = 0.072 P = 0.038 P = 0.790
  n = 14 n = 15 n = 15
  -0.164 0.335 0.016
ΔCSF NGF P = 0.558 P = 0.204 P = 0.953
  n = 15 n = 16 n = 16
  0.802 0.288 0.315
ΔCSF NPY P = 0.001 P = 0.318 P = 0.273
  n = 13 n = 14 n = 14
  -0.165 0.225 -0.119
ΔCSF IL-6 P = 0.573 P = 0.420 P = 0.673
  n = 15 n = 15 n = 15
  -0.164 -0.109 0.103
ΔCSF IL-8 P = 0.558 P = 0.688 P = 0.704
  n = 15 n = 16 n = 16
  -0.156 -0.579 0.329
ΔCSF MMP3 P = 0.594 P = 0.024 P = 0.231
  n = 14 n = 15 n = 15
  1. Median and range (min-max) indicated. Spearmans rho(rs), two-tailed significance (P), and number of subjects (n) are presented.