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Table 4 Cytokine concentrations in supernatants of rheumatoid arthritis synovial fibroblast (RA-SFB) cultures (pg/ml)

From: Cytokine mRNA and protein expression in primary-culture and repeated-passage synovial fibroblasts from patients with rheumatoid arthritis

   RA-SFB
Cytokine Detection limit of the ELISA (pg/ml) First passage (n = 3) Tenth passage (n = 3)
IL-1β 5 Not detectable Not detectable
IL-6 5 15,800 ± 2110 790.0 ± 35.6*
IL-10 1.5 35.7 ± 34.2b 9.0 ± 7.5b
IL-15 1 Not detectable Not detectable
IL-18 94 Not detectable Not detectable
TNF-α 1.7 22.1 ± 1.1 15.1 ± 0.7*
  1. bCytokine detected in only one of three samples. *P ≤ 0.05 in comparison with first-passage RA-SFB.