Characterization of new bone formation in gout: a quantitative site-by-site analysis using plain radiography and computed tomography

Table 2 Site-by-site plain radiography analysis.

		Erosion present, number	Erosion absent, number	OR (95%CI)	P	Erosion score, in eroded joints, mean (SD)	P	JSN present, number	JSN absent, number	OR (95%CI)	P	JSN score, in narrowed joints, mean (SD)	P
Spur	Present	73	3	64.9	<0.0001	4.2 (1.2)	<0.0001	55	14	28.7	<0.0001	2.6 (1.2)	<0.0001
	Absent	197	525	(20.2-208.5)		2.2 (1.3)		58	431	(15.0-54.8)		1.8 (0.9)
Osteophyte	Present	139	28	19.0	<0.0001	3.2 (1.5)	<0.0001	75	58	13.2	<0.0001	2.2 (1.1)	0.65
	Absent	131	500	(12.1-29.7)		2.3 (1.4)		38	387	(8.2-21.2)		2.3 (1.2)
Periosteal NBF	Present	50	1	119.8	<0.0001	3.9 (1.4)	<0.0001	29	7	21.6	<0.0001	2.5 (1.1)	0.08
	Absent	220	527	(16.4-872.9)		2.5 (1.5)		84	438	(9.2-51.0)		2.1 (1.1)
Ankylosis	Present	7	0	30.1	0.0005	5.0 (0.0)	<0.0001	5	0	45.2	0.0003	4.0 (0.0)	<0.0001
	Absent	263	528	(1.7-529.)		2.7 (1.5)		108	445	(2.5-823.6)		2.1 (1.1)
Sclerosis	Present	194	13	101.1	<0.0001	3.2 (1.5)	<0.0001	91	62	25.6	<0.0001	2.4 (1.1)	<0.0001
	Absent	76	515	(54.9-186.3)		1.5 (0.7)		22	383	(14.9-43.7)		1.4 (0.7)

Relationship of new bone formation (NBF) with erosion and joint space narrowing (JSN) (n = 798 joints for erosion and 558 joints for JSN). CI, confidence interval; OR, odds ratio; SD, standard deviation.

ISSN: 1478-6362