Genetic mismatch affects the immunosuppressive properties of mesenchymal stem cells in vitro and their ability to influence the course of collagen-induced arthritis

Table 2 Published studies of MSCs in CIA.

Author, Year	MSC	Route	Cell number	Day of delivery	Outcome
Djouad, 2005	C3H10T1/2	iv	10⁶	0	-
			10⁶	21	-
			4 × 10⁶	0	-
			4 × 10⁶	21	Exacerbation
Augello, 2007	BM C57/Bl/10 or GFP transgenic	ip	5 × 10⁶	21	Amelioration
Choi, 2008	BM DBA/1	iv	10⁶	21, 28, 35	Delayed onset
Gonzalez, 2009	hAdMSC Ad DBA/1 Ad C57/Bl6	ip	10⁶	5 days after disease onset	Amelioration
Schurgers, 2010	BM DBA/1 WT or IFNγ KO	iv or ip	10⁶	1, 16, 23	-

Ad, adipose derived; BM, bone marrow derived; h, human; ip, intraperitoneal; iv, intravenous; KO, knock out; WT, wild type.

ISSN: 1478-6362