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Table 2 Markers of inflammation, Ig and immune response according to smoking status in total study population

From: The effect of smoking and alcohol consumption on markers of systemic inflammation, immunoglobulin levels and immune response following pneumococcal vaccination in patients with arthritis

  Current smokers (N = 88) Non-smokers (never-smoked) (N = 212) Ex-smoker
(N = 202)
Smoking pack-years (mean; SD) 24.5 (13)* --- 16.6 (13)*
CRP g/L (mean) (SD) 10.1 (25)** 5.9 (10)** 5.8 (11)**
ESR mm/hour (mean) (SD) 25.6 (22)*** 19.8 (17)*** 21.4 (19)
IgG g/L (mean) (SD) 9.9 (3) # 10.6 (2) 10.4 (3)
IgA g/L (mean) (SD) 2.6 (1) 2.7 (1) 2.7 (1)
IgM g/L (mean) (SD) 1.2 (0.6) 1.3 (0.9) 1.3 (0.7)
GMC¤ immune response 23F 2.6 ## 3.7 3.3
GMC¤ immune response 6B 1.8 ### 2.4 2.2
  1. GMC¤ = geometric mean concentration of immune response
  2. *P <0.001 compared to ex-smokers (independent sample T-test)
  3. ** P = 0.04 compared to non smokers (never-smoked); p = 0.045 compared to ex-smokers (independent sample T-test)
  4. *** P = 0.023 compared to non-smokers (never-smoked); independent sample T-test
  5. #P = 0.028 compared to non-smokers (never-smoked); independent sample T-test
  6. ## P = 0.028 compared to non-smokers (never-smoked); Mann-Whitney U test
  7. ### P = 0.0042 compared to non-smokers (never-smoked); Mann-Whitney U test