dbSNP identity | Allele/ Geno type | Number of patients with RA (%) | Number of controls (%) | Pvalue | Pvalue after multivariate logistic regression | Pvalue after multiple testing correction (Bonferroni method) | Odds Ratio (%95 CI) | HWE test for case (df = 1) | HWE test for control (df = 1) |
---|---|---|---|---|---|---|---|---|---|
rs7827474 | C | 31(0.059) | 1(0.003) | 3.68E-05 | 3.31E-03 | 5.83E-04 | 20.014257 (2.718505~147.349579) | ||
G | 491(0.941) | 317(0.997) | |||||||
CC | 1(0.004) | 0(0.000 | 0.0002 | 0.000186 | 0.929804 | 0.968272 | |||
CG | 29(0.111) | 1(0.006) | |||||||
GG | 231(0.885) | 158(0.994) | |||||||
rs3808540* | A | 307(0.590) | 196(0.613) | 0.525421 | 0.911852 (0.685840~1.212343) | ||||
G | 213(0.410) | 124(0.388) | |||||||
AA | 91(0.350) | 64(0.400) | 0.506516 | 0.923195 | 0.185552 | ||||
AG | 125(0.481) | 68(0.425) | |||||||
GG | 44(0.169) | 28(0.175) | |||||||
rs11774422 | A | 4(0.008) | 1(0.003) | 0.414051 | 2.425855 (0.269936~21.800669) | ||||
G | 526(0.992) | 319(0.997) | |||||||
AG | 4(0.015) | 1(0.006) | 0.412665 | 0.901484 | 0.968372 | ||||
GG | 261(0.985) | 159(0.994) | |||||||
rs7011926 | A | 287(0.542) | 172(0.541) | 0.985804 | 1.002536 (0.758458~1.325161) | ||||
G | 243(0.458) | 146(0.459) | |||||||
AA | 77(0.291) | 55(0.346) | 0.079064 | 0.86122 | 0.006761 | ||||
AG | 133(0.502) | 62(0.390) | |||||||
GG | 55(0.208) | 42(0.264) | |||||||
rs34456327 | A | 7(0.013) | 312(1.000) | 0.040401 | |||||
G | 7(0.013) | 0(0.000) | |||||||
AA | 257(0.981) | 156(1.000) | 0.221769 | 3.33E-15 | 1 | ||||
AG | 3(0.011) | 0(0.000) | |||||||
GG | 2(0.008) | 0(0.000) | |||||||
rs7821248 | A | 2(0.004) | 1(0.003) | 0.874655 | 1.213178 (0.109552~13.434785) | ||||
G | 516(0.996) | 313(0.997) | |||||||
AA | 1(0.004) | 0(0.000) | 0.323685 | 5.55E-16 | 0.968069 | ||||
AG | 0(0.000) | 1(0.006) | |||||||
GG | 258(0.996) | 156(0.994) | |||||||
rs13276893 | A | 359(0.730) | 218(0.717) | 0.699646 | 1.064841 (0.773866~1.465222) | ||||
G | 133(0.270) | 86(0.283) | |||||||
AA | 122(0.496) | 77(0.507) | 0.238757 | 0.003729 | 0.641532 | ||||
AG | 115(0.467) | 64(0.421) | |||||||
GG | 9(0.037) | 11(0.072) | |||||||
rs2220972 | A | 1(0.002) | 0(0.000) | 0.438632 | |||||
G | 533(0.998) | 320(1.000) | |||||||
AG | 1(0.004) | 0(0.000) | 0.438364 | 0.975544 | 1 | ||||
GG | 266(0.996) | 160(1.000) | |||||||
rs34282382 | A | 502(0.954) | 298(0.949) | 0.725735 | 1.123042 (0.587088~2.148271) | ||||
C | 24(0.046) | 16(0.051) | |||||||
AA | 240(0.913) | 141(0.898) | 0.612061 | 0.521732 | 0.501138 | ||||
AC | 22(0.084) | 16(0.102) | |||||||
CC | 1(0.004) | 0(0.000) | |||||||
rs7840971 | A | 5(0.009) | 1(0.003) | 0.285353 | 3.049713 (0.354681~26.222826) | ||||
G | 523(0.991) | 319(0.997) | |||||||
AA | 2(0.008) | 0(0.000) | 0.511044 | 3.00E-15 | 0.968372 | ||||
AG | 1(0.004) | 1(0.006) | |||||||
GG | 261(0.989) | 159(0.994) | |||||||
rs7841304 | A | 2(0.004) | 1(0.003) | 0.887385 | 1.189516 (0.107391~13.175623) | ||||
G | 496(0.996) | 295(0.997) | |||||||
AG | 2(0.008) | 1(0.007) | 0.887172 | 0.949269 | 0.967107 | ||||
GG | 247(0.992) | 147(0.993) | |||||||
rs7818073 | A | 4(0.008) | 0(0.000) | 0.12006 | |||||
T | 528(0.992) | 320(1.000) | |||||||
AA | 1(0.004) | 0(0.000) | 0.403133 | 4.44E-16 | 1 | ||||
AT | 2(0.008) | 0(0.000) | |||||||
TT | 263(0.989) | 160(1.000) | |||||||
rs7841425 | A | 184(0.365) | 91(0.318) | 0.183639 | 1.232143 (0.905616~1.676401) | ||||
C | 320(0.635) | 195(0.682) | |||||||
AA | 46(0.183)) | 17(0.119) | 0.250595 | 0.000748 | 0.330884 | ||||
AC | 92(0.365) | 57(0.399) | |||||||
CC | 114(0.452) | 69(0.483) |