Table 1 Rheumatoid arthritis autoantigens with relatively high specificity
From: Autoantibody systems in rheumatoid arthritis: specificity, sensitivity and diagnostic value
Antigen | Sensitivity (%) | Specificity (%) |
|---|---|---|
Rheumatoid factor | 70–75 | Also present in other autoimmune diseases, infectious diseases and healthy individuals |
Anti-perinuclear factor/anti-filaggrin/anti-cyclic citrullinated peptide | 50–91 | > 97 |
Sa | ≤ 40 | 85–95 |
Heavy chain binding protein (BiP)/p68 | ≤ 68 | > 97* |
Glucose-6-phosphate isomerase | ≤ 64 | > 95* |