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Table 2 Preclinical alterations of heart, lung and esophageal function in early SSc and UCTD patients

From: Early systemic sclerosis: short-term disease evolution and factors predicting the development of new manifestations of organ involvement

  Early SSc (n= 39) UCTD (n= 37) P
E/A ratio <1* 2/31 (6.5) 1/26 (3.8) ns
DLCO <80% 11/39 (28.2) 10/37 (27) ns
FVC <80% 1/39 (2.6) 1/37 (2.7) ns
Basal LES pressure <15 mmHg 11/36 (30.6) 4/27 (14.8) ns
One or more functional alteration 19/39 (48.7) 14/37 (37.8) ns
  1. *not alternatively explained. All data are expressed as numbers and percentages (in brackets). DLCO, diffusing lung capacity for carbon monoxide; E/A ratio <1, inverted ratio between early (E)/late (atrial = A) ventricular filling velocity; FVC, forced vital capacity; LES, low esophageal sphincter; SSc, systemic sclerosis; UCTD, undifferentiated connective tissue disease