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Table 2 Preclinical alterations of heart, lung and esophageal function in early SSc and UCTD patients

From: Early systemic sclerosis: short-term disease evolution and factors predicting the development of new manifestations of organ involvement

 

Early SSc

(n= 39)

UCTD

(n= 37)

P

E/A ratio <1*

2/31 (6.5)

1/26 (3.8)

ns

DLCO <80%

11/39 (28.2)

10/37 (27)

ns

FVC <80%

1/39 (2.6)

1/37 (2.7)

ns

Basal LES pressure <15 mmHg

11/36 (30.6)

4/27 (14.8)

ns

One or more functional alteration

19/39 (48.7)

14/37 (37.8)

ns

  1. *not alternatively explained. All data are expressed as numbers and percentages (in brackets). DLCO, diffusing lung capacity for carbon monoxide; E/A ratio <1, inverted ratio between early (E)/late (atrial = A) ventricular filling velocity; FVC, forced vital capacity; LES, low esophageal sphincter; SSc, systemic sclerosis; UCTD, undifferentiated connective tissue disease