Figure 1From: Fractional clearance of urate: validation of measurement in spot-urine samples in healthy subjects and gouty patientsFractional clearance of urate CU in gouty patients with incrementally increased doses of allopurinol to achieve target concentrations (Study 1D). Mean age (range) was 56 years (17 to 80 years) (n = 22). The number of patients at each dose level is indicated on the graph.Back to article page