Table 1 Fractional clearance of urate (%) in healthy subjects derived from timed urine collections within a 24-hour period
Subject | Spot am | 12-hour overnight | 2-hour | 4-hour | 6-hour | 24-hour |
|---|---|---|---|---|---|---|
H01 | 8.0 | 5.7 | 9.9 | 9.7 | 7.0 | 7.1 |
H02 | 7.1 | 3.4 | 9.0 | 12.6 | 7.9 | 6.6 |
H03 | 6.3 | 3.0 | 10.6 | 6.8 | 6.7 | 4.8 |
H04 | 6.3 | 5.3 | 8.5 | 6.0 | 8.1 | 6.4 |
H05 | 5.2 | 3.8 | 5.2 | 7.1 | 6.7 | 5.2 |
H06 | 6.3 | 5.3 | 8.5 | 7.9 | 7.0 | 6.4 |
H07 | 8.4 | 6.7 | 14.3 | 8.1 | 7.5 | 7.8 |
H08 | 6.4 | 7.0 | 9.0 | 6.9 | 7.4 | 7.3 |
H09 | 4.3 | 2.2 | 3.0 | 5.1 | 6.1 | 3.8 |
H10 | 10.7 | 11.9 | 15.8 | 16.4 | 12.0 | 11.1 |
H11 | 11.3 | 2.1 | 7.1 | 6.3 | 9.7 | 5.8 |
H12 | 8.8 | 7.3 | 8.5 | 9.5 | 7.7 | 7.9 |
Mean | 7.4 | 5.3 a | 9.1 b | 8.5 | 7.8 | 6.9 b |
95% CI | 6.1 to 8.8 | 3.6 to 7.1 | 6.9 to 11.3 | 6.5 to 10.6 | 7.0 to 8.8 | 5.4 to 8.3 |