Table 3 The effect of allopurinol, probenecid, and the combination on fractional clearance of urate in healthy subjects
Subject | FCU (%) | |||
|---|---|---|---|---|
| Â | Baseline | A | P | A + P |
H01 | 4.5 | 5.7 | 8.3 | 14.9 |
H02 | 8.1 | 8.5 | 25.9 | 24.1 |
H03 | 12.1 | 7.9 | 34.0 | 33.4 |
H04 | 4.8 | 5.4 | 22.6 | 26.2 |
H05 | 8.2 | 7.4 | 22.9 | 31.7 |
H06 | 10.2 | 10.0 | 23.1 | 21.5 |
H07 | 5.3 | 3.9 | 19.6 | 23.8 |
H08 | 2.5 | 5.8 | 16.2 | 21.4 |
H09 | 11.5 | 10.3 | 27.4 | 22.1 |
H10 | 12.5 | 7.5 | 30.8 | 30.1 |
H11 | 7.5 | 6.4 | 17.5 | 22.9 |
Mean | 7.9 | 7.2 | 22.6 | 24.7 |
95% CI | 5.7 to 10.2 | 5.8 to 8.5 | 17.8 to 27.4 | 21.1 to 28.3 |