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Table 2 Hazard ratio (HR) of incident gout by baseline anemia in the ARIC study.

From: Anemia and the onset of gout in a population-based cohort of adults: Atherosclerosis Risk in Communities study

 

No anemia

Anemia

Model

HR (95% CI)

HR (95% CI)

Unadjusted

Reference

2.01 (1.46, 2.76)**

Sex and race adjusted

Reference

1.52 (1.10, 2.12)*

Sex, race and eGFR adjusted

Reference

1.54 (1.11, 2.14)*

Adjusted for confounders1

Reference

1.64 (1.18, 2.28)*

Additionally adjusted for clinical factors2

Reference

1.73 (1.24, 2.41)*

Additionally adjusted for serum urate

Reference

1.83 (1.30, 2.57)**

  1. 1 Confounders: Sex, race, categorical eGFR (CKD-EPI), body mass index (kg/m2) and alcohol intake. 2 Clinical factors: Baseline hypertension, diuretic use, coronary heart disease, and congestive heart failure. * P-value <0.05. ** P-value <0.001. Note: Age was used as the time-scale. Anemia was defined as hemoglobin <13.5 g/dL for men and <12 g/dL for women.