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Table 1 Patient characteristics

From: In vitro glucocorticoid sensitivity is associated with clinical glucocorticoid therapy outcome in rheumatoid arthritis

 

Controls (n = 20)

TREACH (n = 38)

FLARE (n = 37)

Female gender, n (%)

10 (50)

25 (65.8)

25 (67.6)

Age in years, mean (SD)

31.8 (9.7)

53.3 (13.98)a

53.7 (13.40)a

Disease duration in months, median (range)

-

5.4 (2-12)

73.0 (0-414)b

Presence of joint erosions, n (%)

-

10 (26.3)

20 (54.1)c

Anti-CCP positive, n (%)

-

30 (78.9)

24 (85.7)d

Rheumatoid factor (IgM) positive, n (%)

-

31 (81.6)

27 (73.0)

DAS44 at baseline, mean (SD)

-

3.05 (0.92)

3.57 (0.95)c

HAQ-DI at baseline, mean (SD)

-

-

1.43 (0.62)

Use of NSAID, n (%)

-

25 (67.6)

19 (51.4)

Use of methotrexate, n (%)

-

-

22 (59.5)

Use of hydroxychloroquine, n (%)

-

-

11 (29.7)

Use of sulfasalazine, n (%)

-

-

5 (13.5)

Number of DMARDs, median (range)

-

-

1 (0-3)e

Use of anti-TNF-α therapy, n (%)

-

-

5 (13.5)

  1. DAS44, Disease Activity Score, 44 joints; HAQ-DI, Health Assessment Questionnaire Disability Index. aP < 0.001 as compared with healthy controls; bP < 0.001 as compared with tREACH patients; cP < 0.05; danti-CCP was not routinely analyzed; percentage is based on 28 patients with known anti-CCP status; eSeven patients were not using any DMARD at the time of assessment.