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Table 2 Expression of activation and differentiation markers on T cells (CD3+) from peripheral blood (PB) and synovial fluid (SF) of patients with juvenile idiopathic arthritis

From: T-cell activation without proliferation in juvenile idiopathic arthritis

  CD4 CD8
Marker PB SF PB SF
CD69 2.8 9.1*** 3.5 14.6***
CD25 3.7 6.0*** 2.9 3.3*
CD71 2.8 5.0*** 3.1 3.9**
HLA-DR 2.7 19.3*** 3.5 26.7***
CD45RO 27.1 97.1*** 23.6 73.9***
CD45RB 179.4 49.1*** 273.8 142.0***
  1. Values are median fluorescence intensity of the markers (except for CD45RO, which is expressed as % positive) on CD4+ or CD8+ T cells. *P < 0.05, **P < 0.01, ***P < 0.001, versus PB.