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Table 4 Common autoimmune manifestations in common variable immunodeficiency

From: Common variable immunodeficiency - an update

 

Mount Sinai 1999 [3] (n = 248)

Mount Sinai 2011 [38] (n = 473)

DEFI 2010 [62] (n = 311)

AIHA

4.8% (12/248)

7% (33/473)

5.4% (17/311)

ITP

6% (15/248)

14.2% (67/473)

13.2% (41/311)

Neutropenia

<1% (2/248)

<1% (<5/473)

3.2% (10/311)

Rheumatoid arthritis

3.6% (9/248)

3.2% (15/473)

2.6% (8/311)

Vitiligo

NS

<1% (<5/473)

3.9% (12/311)

Sicca syndrome, Sjögren's syndrome

<1% (2/248)

<1% (<5/473)

4.2% (13/311)

Autoimmune thyroiditis, diabetes mellitus,

<1% (2/248)

<1% (<5/473

3.9% (12/311)

multiple sclerosis

   

Alopecia

1.6% (4/248)

1.1% (5/473)

NS

Pernicious anemia

1.2% (3/248)

<1% (<5/473)

NS

Systemic lupus erythematosus

<1% (2/248)

<1% (<5/473)

<1% (1/311)

  1. AIHA, autoimmune hemolytic anemia; ITP, immune thrombocytopenic purpura; NS, not specified.