Accession numbera
|
Name
|
Symbol
|
Ratiob
|
Pvalue
|
Error factorc
|
---|
[P00751]
|
Complement factor B
|
CFAB
|
0.5566
|
0.0064
|
1.397
|
[Q08431]
|
Lactadherin
|
MFGM
|
0.597
|
0.0151
|
1.3855
|
[Q7Z7G0]
|
Target of Nesh-SH3
|
TARSH
|
0.7017
|
0.006
|
1.2209
|
[P09871]
|
Complement C1s subcomponent
|
C1S
|
0.7085
|
0.0007
|
1.1398
|
[P01024]
|
Complement C3
|
CO3
|
0.7241
|
0.0023
|
1.1999
|
[P02751]
|
Fibronectin
|
FINC
|
0.7321
|
0.0006
|
1.1891
|
[P03956]
|
Interstitial collagenase
|
MMP1
|
0.7113
|
0
|
1.0977
|
[P00736]
|
Complement C1r subcomponent
|
C1R
|
0.7734
|
0.0071
|
1.1755
|
[P08253]
|
72 kDa type IV collagenase
|
MMP2
|
0.7759
|
0.0001
|
1.0999
|
[P36222]
|
Chitinase-3-like protein 1
|
CH3L1
|
0.8088
|
0.0216
|
1.4096
|
[P10909]
|
Clusterin
|
CLUS
|
0.8224
|
0.05
|
1.2162
|
[P08254]
|
Stromelysin-1
|
MMP3
|
0.8256
|
0.0086
|
1.1378
|
[P07093]
|
Glia-derived nexin
|
GDN
|
1.2894
|
0.0031
|
1.1664
|
[O00391]
|
Sulfhydryl oxidase 1
|
QSOX1
|
1.3064
|
0.0382
|
1.2709
|
[Q92954]
|
Proteoglycan 4
|
PRG4
|
1.4393
|
0.05
|
1.445
|
[P98066]
|
TNF-inducible gene 6 protein
|
TSG6
|
1.7773
|
0.0007
|
1.3371
|
[P61769]
|
Beta-2-microglobulin
|
B2MG
|
2.1652
|
0.0125
|
1.4553
|
[P07996]
|
Thrombospondin-1
|
TSP1
|
89.1678
|
0
|
>2
|
- Extracellular proteins identified by SILAC and liquid chromatography-mass spectrometry analysis as modulated by CS treatment in IL-1β-stimulated chondrocytes. aProtein accession number according to the SwissProt and TrEMBL databases. bAverage SILAC ratios (n = 3) that represent the relative protein abundance in CS-treated versus untreated cells, calculated by Protein Pilot 3.0 software (ABSciex). P ≤ 0.05 was accepted. cError factor of the quantification (measure of the error in the average quantification ratio as calculated by Protein Pilot 3.0 software).