Biomechanical factors and physical examination findings in osteoarthritis of the knee: associations with tissue abnormalities assessed by conventional radiography and high-resolution 3.0 Tesla magnetic resonance imaging

Table 4 Regression analyses^a of association between tissue abnormalities detected by CR and/or MRI and biomechanical factors

		Quadriceps strength (Nm/kg)	Hamstrings strength (Nm/kg)	Proprioceptive accuracy (degrees)	Varus-valgus laxity (degrees)
Conventional radiography
JSW^b	MTF	-0.12 (0.16)	0.02 (0.84)	-0.03 (0.78)	-0.22 (0.02)
	LTF	-0.07 (0.37)	-0.03 (0.71)	-0.08 (0.42)	0.26 (<0.01)
	PF	-0.18 (0.03)	0.09 (0.28)	-0.03 (0.80)	-0.14 (0.13)
Osteophyte^b	MTF	-0.03 (0.69)	0.04 (0.66)	-0.10 (0.31)	0.07 (0.47)
	LTF	-0.06 (0.51)	0.06 (0.46)	-0.05 (0.63)	0.26 (<0.01)
	PF	-0.09 (0.30)	0.06 (0.44)	-0.09 (0.38)	-0.08 (0.37)
Magnetic resonance imaging
Cartilage integrity	MTF	-0.15 (0.07)	0.00 (0.97)	0.11 (0.25)	-0.22 (0.02)
	LTF	-0.05 (0.55)	0.09 (0.30)	0.05 (0.61)	0.07 (0.44)
	PF	-0.17 (0.04)	0.10 (0.24)	-0.02 (0.86)	-0.11 (0.23)
Osteophytes	MTF	-0.05 (0.56)	0.11 (0.18)	0.08 (0.43)	-0.08 (0.36)
	LTF	-0.08 (0.33)	0.05 (0.58)	0.02 (0.88)	0.02 (0.87)
	PF	-0.12 (0.15)	-0.01 (0.95)	-0.03 (0.77)	-0.17 (0.06)
BML	MTF	0.03 (0.76)	0.12 (0.13)	0.16 (0.11)	-0.06 (0.48)
	LTF	-0.05 (0.54)	0.12 (0.13)	-0.05 (0.62)	0.12 (0.18)
	PF	0.01 (0.91)	0.16 (0.06)	-0.17 (0.08)	-0.12 (0.19)
Effusion^c		-0.16 (0.05)	-0.08 (0.34)	0.11 (0.26)	0.08 (0.40)
Synovitis^d		-0.21 (0.01)	-0.11 (0.17)	0.03 (0.76)	-0.02 (0.83)

Data presented as standardized regression coefficient β (P value). Significant associations (P <0.05) in bold. BML, bone marrow lesion; CR, conventional radiography; JSW, joint space width; LTF, lateral tibiofemoral compartment; MRI, magnetic resonance imaging; MTF, medial tibiofemoral compartment; PF: patellafemoral compartment. ^aAdjusted for age, gender and duration of knee symptoms. ^bDefinite/severe abnormality compared with none/mild abnormality (reference group). ^cMedium/large effusion compared with no/small effusion (reference group). ^dPresence of synovitis in at least one region compared with absence of synovitis (reference group).

ISSN: 1478-6362