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Table 2 Predictors of mortality in CTD-PAH on univariate analysis

From: Predictors of mortality in connective tissue disease-associated pulmonary arterial hypertension: a cohort study

Variable Unadjusted HR (95% CI) P
Male sex 3.42 (1.27 to 9.22) 0.02
Age at PAH diagnosis, years 1.01 (0.98 to 1.04) 0.72
Underlying CTD (SSc) 1.27 (0.44 to 3.66) 0.66
WHO FC at baseline 3.64 (1.32 to 10.01) 0.01
Baseline 6MWD* 0.70 (0.52 to 0.95) 0.02
Pericardial effusion 2.83 (1.12 to 7.12) 0.03
mPAP at baseline, mmHg 1.01 (0.98 to 1.05) 0.42
mRAP at baseline, mmHg 1.11 (1.02 to 1.19) 0.01
Warfarin therapy 0.26 (0.11 to 0.66) 0.004
Combination therapy 0.38 (0.16 to 0.92) 0.03
  1. *hazard ratio relates to each 100 metres increase in 6MWD
  2. 6MWD, six minute walk distance; CTD, connective tissue disease; HR, hazard ratio; mPAP, mean pulmonary artery pressure; mRAP, mean right atrial pressure; PAH, pulmonary arterial hypertension; SSc, systemic sclerosis; WHO FC, World Health Organization Functional Class