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Table 3 Independent predictors of mortality in CTD-PAH, determined using multivariable proportional hazards regression analysis

From: Predictors of mortality in connective tissue disease-associated pulmonary arterial hypertension: a cohort study

Variable Adjusted HR (95% CI) P
WHO FC at baseline 3.42 (1.25 to 9.36) 0.04
mRAP at baseline, mmHg 1.13 (1.04 to 1.24) 0.007
Baseline 6MWD*, m 0.64 (0.43 to 0.97) 0.04
Pericardial effusion 3.39 (1.07 to 10.68) 0.04
Warfarin therapy 0.20 (0.05 to 0.78) 0.02
Combination therapy 0.20 (0.05 to 0.83) 0.03
  1. *hazard ratio relates to each 100 metres increase in 6MWD
  2. 6MWD, six minute walk distance; 95% CI, 95% confidence interval; HR, hazard ratio; mRAP, mean right atrial pressure; WHO FC, World Health Organization functional class