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Figure 1 | Arthritis Research & Therapy

Figure 1

From: Restoration of regulatory and effector T cell balance and B cell homeostasis in systemic lupus erythematosus patients through vitamin D supplementation

Figure 1

Safety and clinico-biological efficacy of vitamin D supplementation in SLE patients. Time evolution of serum 25(OH)D levels (A), disease activity assessed by the SLEDAI (B), and anti-dsDNA levels (C). Serum 25(OH)D levels dramatically increased with vitamin D supplementation, while anti-dsDNA levels decreased. The dotted line in panel A indicates normal values. Box plots indicate median, interquartile ranges, minimum and maximum values. Histograms indicate mean ± standard error of the mean (SEM). *P < 0.05, **P < 0.01, ***P < 0.001 versus Day 0; Wilcoxon test.

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