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Figure 2 | Arthritis Research & Therapy

Figure 2

From: Osteogenesis and osteoclast inhibition in rheumatoid arthritis patients treated with bisphosphonates alone or in combination with pitavastatin over an 18-month follow-up after more than 4 years of treatment with bisphosphonates

Figure 2

Percentage changes in bone mineral density (BMD) of the lumbar spine measured by dual-energy x-ray absorptiometry (DXA) at 6, 12 and 18 months after the start of treatment in the bisphosphonate (Bis) and Bis + statin groups. Circles represent the Bis group and triangles represent the Bis + statin group. Significant increases in BMD of the lumbar spine were observed at 6, 12 and 18 months in the Bis + statin group, but in the Bis group a significant increase was only observed at 18 months. *P < 0.05, **P < 0.01, ***P < 0.001, for comparison to baseline for each group.

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