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Figure 4 | Arthritis Research & Therapy

Figure 4

From: Osteogenesis and osteoclast inhibition in rheumatoid arthritis patients treated with bisphosphonates alone or in combination with pitavastatin over an 18-month follow-up after more than 4 years of treatment with bisphosphonates

Figure 4

Percentage changes in serum N-terminal telopeptide of type I collagen (NTX) at 6, 12 and 18 months after the start of treatment in the bisphosphonate (Bis) and Bis + statin groups. Circles represent the Bis group and triangles represent the Bis + statin group. A significant decrease in serum NTX was observed at 12 months in the Bis group, but in the Bis + statin group, serum NTX was up-regulated during the follow-up period except at 6 months. *P < 0.05, **P < 0.01, for comparison to baseline for each group.

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