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Figure 6 | Arthritis Research & Therapy

Figure 6

From: Osteogenesis and osteoclast inhibition in rheumatoid arthritis patients treated with bisphosphonates alone or in combination with pitavastatin over an 18-month follow-up after more than 4 years of treatment with bisphosphonates

Figure 6

Percentage changes in serum C- terminal propeptide of type I procollagen (PICP) at 6, 12 and 18 months after the start of treatment in the bisphosphonate (Bis) and Bis + statin groups. A significant increase in serum PICP was observed at 6 months in the Bis and Bis + statin group. On the other hand, in the Bis + statin group serum PICP tends to increase after 12 months. *P < 0.05, **P < 0.01, for comparison to baseline for each group.

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