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Table 1 Classification of histone deacetylases and their inhibitors

From: Epigenetic contributions in the development of rheumatoid arthritis

Class Member Inhibitors References
I HDAC1 TSA, SAHA, ITF2357, FK228, VPA, MS-275 [27, 40, 4751]
  HDAC2 TSA, SAHA, ITF2357, FK228, VPA  
  HDAC3 TSA, SAHA, ITF2357, FK228, VPA, MS-275, MI192  
  HDAC8 TSA, SAHA, ITF2357, FK228, VPA  
II HDAC4 TSA, SAHA, ITF2357, VPA [27, 47, 49, 50]
  HDAC5 TSA, SAHA, ITF2357, VPA  
  HDAC6 TSA, SAHA, ITF2357, VPA  
  HDAC7 TSA, SAHA, ITF2357, VPA  
  HDAC9 TSA, SAHA, ITF2357, VPA  
  HDAC10 TSA, SAHA, ITF2357, VPA  
III SIRT1 to SIRT7 Nicotinamide [52]
IV HDAC11 -  
  1. Human histone deacetylases (HDACs) were classified into four subgroups. HDAC inhibitors summarized in the text are listed. SAHA, suberoylanilide hydroxamic acid; SIRT, sirtuin; TSA, trichostatin A; VPA, valproic acid.